allergic asthma — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8239	Cromoglicic acid		Others
	Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.		Others
TN1416	Ayanin		IL Receptor , P450 , PARP , PDE
	Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio...		IL Receptor , P450 , PARP , PDE
T9926	Omalizumab		Others
	Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE)		Others
T9043	AS1810722		P450 , STAT
	AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate f...		P450 , STAT
TN2244	Sulfuretin		NF-κB , Autophagy
	Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr...		NF-κB , Autophagy
T0211	Azelastine	Azelastina,Astelin,Azelastinum	SARS-CoV , Histamine Receptor
	Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.		SARS-CoV , Histamine Receptor
T5310	TR-14035	MDK-1191	Integrin
	TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).		Integrin
T0211L	Azelastine hydrochloride	Optivar,Azelastine HCl,Allergodil,Astelin	SARS-CoV , Histamine Receptor
	Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity.		SARS-CoV , Histamine Receptor
T0188	Fluticasone (propionate)	CCI-187881,Fluticasone propionate	Glucocorticoid Receptor , Virus Protease , Estrogen/progestogen Receptor , Phospholipase , Endogenous Metabolite
	Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist.
T15772	Lodoxamide tromethamine	U-42585E	Histamine Receptor
	Lodoxamide tromethamine is a mast cell stabilizer with anti-allergic properties and can be used in studies about the treatment of asthma and allergic conjunctivitis.		Histamine Receptor
T2270	Trans-Tranilast	Tranilast trans-	RAAS
	Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993....		RAAS
T1030	Triprolidine hydrochloride monohydrate	Triprolidine hydrochloride	Histamine Receptor
	Triprolidine hydrochloride monohydrate is a histamine H1 antagonist used in allergic rhinitis, asthma.		Histamine Receptor
TMA1570	Sappanone A		NF-κB , Nrf2
	Sappanone A is a high isoflavanone that exhibits anti-inflammatory effects by modulating Nrf2.Sappanone A attenuates allergic airway inflammation in ovalbumin-induced asthma.		NF-κB , Nrf2
T1531	Mometasone furoate	Sch32088	Glucocorticoid Receptor
	Mometasone furoate (Sch32088) is a pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for ski...		Glucocorticoid Receptor
T1553	Chlorpheniramine maleate	NCI-C55265,Chlorphenamine maleate	Histamine Receptor
	Chlorpheniramine maleate (NCI-C55265) is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma.		Histamine Receptor
T68128	Picumast
	Picumast shows antiallergic activity and can be utilized in the treatment of asthma. Picumast may be used in the treatment of therapeutic allergic airway diseases.
T2392	Nafamostat mesylate	FUT-175	Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease
	Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
T4566	Lodoxamide	Lodoxamidum	GPR , Histamine Receptor
	Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis.		GPR , Histamine Receptor
T14377	AZD5423		Glucocorticoid Receptor
	AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.		Glucocorticoid Receptor
T2396	Ramatroban	BAY u3405	GPR , Prostaglandin Receptor , PPAR
	Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. It has been used in trials studying the treatment of Asthma.		GPR , Prostaglandin Receptor , PPAR